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The nurse notes hyperventilation in a client with a thermal injury. She recognizes that this may be a reaction to which of the following medications if applied in large amounts?

The nurse notes hyperventilation in a client with a thermal injury. She recognizes that this may be a reaction to which of the following medications if applied in large amounts?
A . Neosporin sulfate
B . Mafenide acetate
C . Silver sulfadiazine
D . Povidone-iodine

Answer: B

Explanation:

(A) The side effects of neomycin sulfate include rash, urticaria, nephrotoxicity, and ototoxicity.

(B) The side effects of mafenide acetate include bone marrow suppression, hemolytic anemia, eosinophilia, and metabolic acidosis. The hyperventilation is a compensatory response to the metabolicacidosis.

(C) The side effects of silver sulfadiazine include rash, itching, leukopenia, and decreased renal function.

(D) The primary side effect of povidone- iodine is decreased renal function.

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