For what minimum period should spironolactone be discontinued before this test?

A 62-year-old woman with persistent hypertension attended the clinic for review. She had

no previous medical history of note and was taking amlodipine, ramipril, bendroflumethiazide, spironolactone and doxazosin. Her blood pressure was raised at 160/100 mmHg.

Investigations:

serum sodium138 mmol/L (137C144)

serum potassium3.8 mmol/L (3.5C4.9)

A blood test for renin and aldosterone concentration was being considered.

For what minimum period should spironolactone be discontinued before this test?
A . 72 h
B . 1 week
C . 2 weeks
D . 6 weeks
E . 8 weeks

View Answer

Answer: D