The presence of which feature would most increase the likelihood of malignancy?

A 25-year-old woman presented with a solitary nodule in the right lobe of her thyroid gland.

Investigations:

serum thyroid-stimulating hormone0.45 mU/L (0.4C5.0)

serum free T420.7 pmol/L (10.0C22.0)

The presence of which feature would most increase the likelihood of malignancy?
A . elevated serum thyroglobulin concentration
B . high titre of thyroid peroxidase antibodies
C . increased peripheral vascularity of nodule on Doppler ultrasound
D . microcalcification seen within the nodule on ultrasound scan
E . size of nodule >1.0 cm in maximum diameter

View Answer

Answer: D